[Corresponding Author’s Article]

5. Christyani G, Carswell M, Qin S, Kim W. An Overview of Advances in Rare Cancer Diagnosis and Treatment. International Journal of Molecular Sciences. 2024

4. Qu Y, Qin S, Yang Z, Li Z, Liang Q, Long T, Wang W, Zeng D, Zhao Q, Dai Z, Ni Q, Zhao F, Kim W*, Hou J*. Targeting the DNA repair pathway for breast cancer therapy: Beyond the molecular subtypes.

Biomedicine & Pharmacotherapy. 2023

3. Qin S, Kitty I, Hao Y, Zhao F*, Kim W*. Maintaining Genome Integrity: Protein Kinases and Phosphatases Orchestrate the Balancing Act of DNA Double-Strand Breaks Repair in Cancer. International

Journal of Molecular Sciences. 2023

2. Moon J, Kitty I, Renata K, Qin S, Zhao F*, Kim W*. DNA Damage and Its Role in Cancer Therapeutics. International Journal of Molecular Sciences. 2023

1. Chen L, Hou J, Guo Q, Zeng X, Deng M, Zhao F, Wu M, Tu X, Kloeber J, Huang J, Luo K, Yin P, Kim W*, Lou Z*. LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous

recombination-mediated DNA double strand break repair. Clinical and Translational Medicine. 2021 

[First Author’s Articles]

12. Zhao F*, Kim W*, Lou Z. Yuan J. ASTE1 Orchestrates Shieldin Complex Mediated DNA Repair by Attenuating End Resection. Nature Cell Biology. 2021 (IF 28.824)

11. Kim W*, Zhao F*, Gao H, Qin S, Deng M, Kloeber J, Huang J, Zhou Q, Guo G, Gao M, Tu X, Zeng X, Zhu S, Wu Z, Yin P, Kaufmann S, Luo K, Lou Z. USP13 regulates the replication stress response by deubiquitinating TopBP1. DNA repair. (Amst). 2021 (IF 4.913)

10. Zhao F*, Kim W*, Kloeber JA, Lou Z. DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells. Experimental and Molecular Medicine. 2020 (IF 8.718)

9. Kim W, Zhao F, Wu R, Nowsheen S, Huang J, Zhou Q, Qin S, Chen Y, Deng M, Guo G, Luo K, Yuan J, Lou Z. Zinc finger protein 161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex. Nature Communications. 2019 (IF 14.919)

8. Kim W, Ryu J, Kim JE. CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells. International Journal of Molecular Sciences. 2019 (IF 5.923)

7. Kim W, Pyo J, Byeong-Joo Noh, Joo-Won Jeong, Juhie Lee, Kim JE. CCAR2 negatively regulates IL-8 production in cervical cancer cells. Oncotarget. 2017

6. Kim W, Cheon MG, Kim JE. Mitochondrial CCAR2/DBC1 and its binding partner Hsp60 protect neuroblastoma cells from mitochondrial stress. Biochemical and Biophysical Research Communications. 2017 (IF 3.575)

5. Kim W, Jeong JW, Kim JE. CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells. Tumor Biology. 2014

4. Kim W, Choi MJ, Kim JE. The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle. Cell Cycle. 2014 (IF 4.534)

3. Kim W, Kim JE. Sirtuin 7 is an emerging sirtuin: Deciphering newer roles. Journal of Physiology and Pharmacology. 2013 (IF 3.011)

2. Kim W, Kim JE. Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage. Cancer Letters. 2013 (IF 8.679)

1. Kim W, Park G, Kim R, Park JW, Kim JE. The deficiency of H3K79 histone methyltransferase DOT1L inhibits cell proliferation. Journal of Biological Chemistry. 2012 (IF 5.157)

[Co-author’s Articles]

20. Huang J, Wu C, Kloeber JA, Gao H, Gao M, Zhu Q, Chang Y, Zhao F, Guo G, Luo K, Dai H, Liu S, Huang Q, Kim W, Zhou Q, Zhu S, Wu Z, Tu X, Yin P, Deng M, Wang L, Yuan J, Lou Z. SLFN5-mediated chro         

       matin dynamics sculpt higher-order DNA repair topology. Molecular Cell. 2023

19. Zeng X, Zhao F, Cui G, Zhang Y, Deshpande RA, Chen Y, Deng M, Kloeber JA, Shi Y, Zhou Q, Zhang C, Hou J, Kim W, Tu X, Yan Y, Xu Z, Chen L, Gao H, Guo G, Liu J, Zhu Q, Cao Y, Huang J, Wu Z, Zhu S,

       Yin P, Luo K, Mer G, Paull TT, Yuan J, Tao K, Lou Z. METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma.

      Nature Cancer. 2022

18. Qin S, Gao H, Kim W, Zhang H, Gu Y, Kalari KR, Sinnwell JP, Scholz JA, Xie F, Yin P, Yu J, Qin B, Zhuang Y, Wei L, Tan W, Bryce AH, Weinshilboum RM, Wang L. Biomarkers for Predicting Abiraterone

      Treatment Outcome and Selecting Alternative Therapies in Castration-Resistant Prostate Cancer. Clinical Pharmacology & Therapeutics. 2022

17. Zhang Y, Yang Q, Zeng X, Wang M, Dong S, Yang B, Tu X, Wei T, Xie W, Zhang C, Guo Q, Kloeber JA, Cao Y, Guo G, Zhou Q, Zhao F, Huang J, Liu L, Zhang K, Wang M, Yin P, Luo K, Deng M, Kim W, Hou J,

      Shi Y, Zhu Q, Chen L, Hu S, Yue J, Pi G, Lou Z. MET Amplification Attenuates Lung Tumor Response to Immunotherapy by Inhibiting STING. Cancer Discovery. 2021

16. Qin S, Ingle JN, Kim W, Gao H, Weinshilboum RM, Wang L. ZNF423 modulates the AMP-activated protein kinase pathway and metformin response in a single nucleotide polymorphisms, estrogen

      and selective estrogen receptor modulator dependent fashion. Pharmacogenetics and Genomics. 2021

15. Guo G, Gao M, Gao X, Zhu B, Huang J, Tu X, Kim W, Zhao F, Zhou Q, Zhu S, Wu Z, Yan Y, Zhang Y, Zeng X, Zhu Q, Yin P, Luo K, Sun J, Deng M, Lou Z. Reciprocal regulation of RIG-I and XRCC4 connects 

       DNA repair with RIG-I immune signaling. Nature Communications. 2021

14. Gao M, Guo G, Huang J, Hou X, Ham H, Kim W, Zhao F, Tu X, Zhou Q, Zhang C, Zhu Q, Liu J, Yan Y, Xu Z, Yin P, Luo K, Weroha J, Deng M, Billadeau DD, Lou Z. DOCK7 protects against replication stress

      by promoting RPA stability on chromatin. Nucleic Acids Research. 2021

13. Zhu S, Chen Z, Jiang D, Wang R, Cheng X, Li D, Xv Q, Zhao F, Kim W, Guo G, Zhao C, Lou Z, Liu H. Mixed-lineage leukemia protein modulates the loading of let-7a onto AGO1 by recruiting RAN.

       Haematologica. 2021

12. Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z. The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through

       PrimPol stabilization. Nucleic Acids Research. 2020

11. Gao M, Guo G, Huang J, Kloeber JA, Zhao F, Deng M, Tu X, Kim W, Zhou Q, Zhang C, Yin P, Luo K, Lou Z. USP52 regulates DNA end resection and chemosensitivity through removing inhibitory

      ubiquitination from CtIP. Nature Communications. 2020

10. Huang J, Zhou Q, Gao M, Nowsheen S, Zhao F, Kim W, Zhu Q, Kojima Y, Yin P, Zhang Y, Guo G, Tu X, Deng M, Luo K, Qin B, Machida Y, Lou Z. Tandem Deubiquitination and Acetylation of SPRTN Pro

        motes DNA-Protein Crosslink Repair and Protects against Aging. Molecular Cell. 2020

9. Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J. The bromodomain containing protein BRD-9 orchestrates

     RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair. Nature Communications. 2020

8. Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, Nowsheen S, Wu C, Li Y, Li L, Kim W, Zhou Q, Huang J, Liu J, Zhang C, Guo G, Deng M, Tu X, Gao X, Liu Z, Chen Y, Lou Z, Luo K, Yuan J. CHK2-FOXK axis pro

     motes transcriptional control of autophagy programs. Science Advances. 2020

7. Song Z, Tu X, Zhou Q, Huang J, Chen Y, Liu J, Lee S, Kim W, Nowsheen S, Luo K, Yuan J, Lou Z. A novel UCHL3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homolog

     ous recombination-mediated DNA double strand break repair. Cell Death & Disease. 2019

6. Wu J, Chen Y, Geng G, Li L, Yin P, Nowsheen S, Li Y, Wu C, Liu J, Zhao F, Kim W, Zhou Q, Huang J, Guo G, Zhang C, Tu X, Gao X, Lou Z, Luo K, Qiao H, Yuan J. USP39 regulates DNA damage response

    and chemo-radiation resistance by deubiquitinating and stabilizing CHK2. Cancer Letters. 2019

5. Pyo J, Ryu J, Kim W, Choi JS, Jeong JW, Kim JE. The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression. International Journal of Molecular Sciences. 2018

4. Min YH, Kim W, Kim JE. The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation. Oncotarget. 2016

3. Lee SD, Kim W, Jeong JW, Park JW, Kim JE. AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia. Cancer Letters. 2016

2. Choi M, Kim W, Cheon MG, Lee CW, Kim JE. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells.

    Cancer Letters. 2015

1. Cheon MG, Kim W, Choi M, Kim JE. AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells. Cancer Letters. 2015