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Faculty

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Choon-sik Park image

Kae Won Cho

Ph.D.

Associate Professor, Director of SIMS Research Planning Division

Obesity, Type 2 Diabetes, Immunometabolism, Adipose Tissue, Macrophages

  • Biography

       B.S. in Animal Science, Korea University, Korea

       M.S. in Biotechnology, Korea University, Korea

       Ph.D. in Nutritional Program, Purdue University, USA

       Postdoctoral Fellow, University of Michigan Medical School, USA

       Staff Scientist, University of Michigan Medical School, USA

       Assistant Professor, Soonchunhyang Institute of Medi-bio Science(SIMS), Soonchunhyang University, Korea
       Associate Professor, Soonchunhyang Institute of Medi-bio Science(SIMS), Soonchunhyang University, Korea

  • Research Interest

       Obesity, Type 2 Diabetes, Immunometabolism, Adipose Tissue, Macrophages

       1. Adipose tissue inflammation and the development of metabolic disease

       2. Molecular mechanisms for adipose tissue macrophage polarization, recruitment and proliferation during obesity

       3. Epigenetic mechanisms linking chronic inflammation to metabolic disease development

       4. Identification and characterization of novel regulatory molecules in insulin sensitivity

  • Selected Publication

       1. Cho KW, Morris DL, Delproposto JL, Geletka LM, Zamarron B, Marintez-Santibanez G, Meyer KA, Singer K, O’Rourke RW, Lumeng CN.
           An MHC II-Dependent Activation Loop between Adipose tissue Macrophages and CD4+ T cells Controls Obesity-Induced Inflammation.
           (2014) Cell Reports. 9: 605-617.

       2. Cho KW, Morris DL, Lumeng CN. Flow cytometry analyses of adipose tissue macrophages. (2014) Methods Enzymol. 537:297-314.

       3. Morris DL, Cho KW, Delproposto JL, Oatment KE, Geletka LM, Marinez-Santibanez G, Singer K, Lumeng CN. Adipose tissue macrophages
           function as antigen presenting cells and regulate adipose tissue CD4+ T cells in mice. (2013) Diabetes 62: 2762-72.

       4. Cho KW, Zhou Y, Liang S, Rui L. Lipocalin-13 regulates glucose metabolism by both insulin-dependent and independent mechanisms. (2011)
           Mol Cell Biol. 31:450-7.

       5. Sheng L, Cho KW, Zhou Y, Shen H, Rui L (2011) Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and
           stimulating fatty acid beta-oxidation. J Biol Chem. 286: 38128-35.