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Faculty

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Choon-sik Park image

Kiyoung Kim

Ph.D.

Associate Professor

Neurodegenerative Disease, Protein Aggregation, Post-translational Modification, Mitochondria Function

  • Biography

       B.S. in Biology, Dong-A University, Korea

       M.S. and Ph.D. in Biological Science, Seoul National University, Korea

       Postdoctoral Fellow, Biological Science, Seoul National University, Korea

       Assistant Professor, Soonchunhyang University, Korea
       Associate Professor, Soonchunhyang University, Korea

  • Research Interest

       1. Molecular mechanisms for Amyotrophic Lateral Sclerosis (ALS) pathogenesis

       2. Protein aggregation and degradation in neuronal cells

       3. Mitochondrial dysfunction in neurodegenerative disease

       4. Stress-induced post-translational modification (PTM) of DNA/RNA-binding proteins

       5. Development and analyses of Drosophila model for human disease

  • Selected Publication

       1. Kang, H.Y#., Kim, H.J#., Kim, K#., Oh, S.I., Yoon, S., Kim, J., Park, S., Cheon, Y., Her, S., Lee, M., Lu, B., Lee, S. (2020) Actin-
           microtubule crosslinker Pod-1 tunes PAR-1 signaling to control synaptic development and tau-mediated synaptic toxicity.
    Neurobiol.
           Aging.
    Epub. 

       2. Cha, S.J., Choi, H.J., Kim, H.J., Im, D.S., Kim, K. (2020) Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-
           induced amyotrophic lateral sclerosis.
    Insect. Mol. Biol. 29, 56-65.  

       3. Cha, S.J., Choi, H.J., Do, H.A., Lee, M., Kim, K. (2019) The Drosophila model: Exploring novel therapeutic compounds against
           neurodegenerative diseases.
    Antioxidants. 8, 623.  

       4. Lee, S., Jeon, Y.M., Cha, S.J., Kim, S., Kwon, Y., Jo, M., Jang, Y.N., Lee, S., Kim, J., Kim, S.R., Lee, K.J., Lee, S.B., Kim, K#., Kim,
           H.J
    #. (2019) PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies. Autophagy.
          
    Epub. 

       5. Kim, Y., Kim, H.J., Cha, S.J., Choi, H.J., Kim, H., Lee, S., Jeon, Y.M., Lee, M., Lee, S., Kim, K. (2019) Genetic activation of parkin
           resuces TAF15-induced neurotoxicity in a Drosophila model of amyotrophic lateral sclerosis.
    Neurobiol. Aging. 73, 78-73.